Muskelin regulates actin-dependent synaptic changes and intrinsic brain activity relevant to behavioral and cognitive processes.

The initial response induced by the novel object revealed a marginally significant reduction in the time taken to approach the object in Mkln1 –/– mice (Supplementary Fig. 2f ); the lower neophobic reaction to novelty might reflect decreased perception of risk 18 or increased novelty-seeking behavior.

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