Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation.

These CpGs revealed a highly significant overlap for iMSCs and iHPCs (hypergeometric distribution; exon 19 −/−: P < 10 −60 , exon 23 −/− : P < 10 −33 ), and for exon 19 −/− and exon 23 −/− (iMSCs: P < 10 −36 , iHPCs: P < 10 −38 ) (Fig. 4 c).

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