The approach to lower the prescription dose to ensure critical structure dose limits may, on the other hand, seriously compromises TCP, which may be significant if the overall 5 mm safety margin does not compensate for all treatment errors and a lower BED10 (e.g. lower or close to 105 Gy 10 ) is used [ 25 ].
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Comparison of 3D and 4D Monte Carlo optimization in robotic tracking stereotactic body radiotherapy of lung cancer.
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