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Protective Effects of Engineered <i>Lactobacillus crispatus</i> on Intrauterine Adhesions in Mice <i>via</i> Delivering CXCL12.

Front Immunol · 2022 · PMC9207254 · PMID 35734171

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an increasing trendno p-value reported
2.89, P < 0.05) showed an increasing trend compared with the control group, whereas treatment with L. crispatus and L. crispatus -pMG36e-mCXCL12 reversed this trend and restored the expression levels of TGF-β1, p−Smad2 and p−Smad3 in the NDT group to 4.62, 3.18 and 1.69 and in the EDT group to 3.52, 1.55 and 1.27, respectively.

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