Infectious virus in the brain was detected from 4 dpi onwards in an increasing trend, with the highest loads detected by 6 and 7 dpi, as expected. 30 Interestingly, no significant difference in terms of viral load was observed in the brain at the latest stage regardless of the viral inoculum dose.
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Chronological brain lesions after SARS-CoV-2 infection in hACE2-transgenic mice.
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