HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies in Lebanese and their relatedness to neighboring and distant populations.

BMC Genomics · 2022 · PMC9208108 · PMID 35725365

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an overall trendno p-value reported

Significant differences were noted between the observed and expected homozygotes for the DRB1 ( P = 0.033) and DQB1 ( P = 0.019) loci, indicating an overall trend away from the null hypothesis of neutral evolution, suggesting that the allele frequency distributions at all loci were shaped by balancing selection.

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