highly significantP =6.01×10 −9
This variant in TMEM9 (rs6667912) was also highly significant in the European subgroup analysis (odds ratio [95% CI], 1.39 [1.24–1.55]; P =6.01×10 −9 ; Figure S2 ) and was significantly associated with a skeletal muscle splicing quantitative trait loci in TMEM9 23 ( P =1.1×10 −8 ; Table S2 ).