Trends of Dispensed Opioids in Catalonia, Spain, 2007-19: A Population-Based Cohort Study of Over 5 Million Individuals.

Front Pharmacol · 2022 · PMC9213744 · PMID 35754470

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an increasing trendno p-value reported

Strong opioids such as fentanyl, morphine and oxycodone were more frequently indicated for cancer, however, there is an increasing trend of use of these strong opioids to treat non-cancer medical conditions; For example, the non-cancer indications for morphine merely comprised 29% of any pain-related medical conditions in 2007, but this figure gradually increased to 60% in 2019.

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