The Biota orientalis, oil extract Epiitalis<sup>®</sup>, is efficacious at reducing the symptoms of knee osteoarthritis: a pilot, multi-site, dose-ranging, randomized, blinded, placebo-controlled trial.

Inflammopharmacology · 2022 · PMC9216293 · PMID 35732989

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highly significantno p-value reported

Although the data did not demonstrate a dose response relationship, at study end each hBO dose resulted in robust and highly significant reductions in knee pain in comparison to the placebo group.

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