Barely Significant
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Detoxification Role of Metabolic Glutathione S-Transferase (GST) Genes in Blood Lead Concentrations of Jamaican Children with and without Autism Spectrum Disorder.

Genes (Basel) · 2022 · PMC9222697 · PMID 35741737

Europe PMCDOI
1
hedged sentence
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

marginally significantp = 0.07so close (0.05 < p ≤ 0.1)
Although our previous study did not find any significant interactions between BPbCs and genotypes for any of the aforementioned three GST genes in relation to ASD status, using different conditional logistic regression (CLR) models, (all p for interaction between BPbCs and each of the GST genes > 0.49), a marginally significant interactive association of GSTP1 with a mixture of Pb, Hg, and Mn was detected ( p = 0.07) based on a negative association generalized weighted quantile sum (gWQS) model [ 40 ].

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