Transcription Regulation of Cell Cycle Regulatory Genes Mediated by NtrX to Affect Sinorhizobium meliloti Cell Division

Contrary to these results, the transcripts of ctrA showed an increasing trend in the SmLL1 cells relative to Sm1021, and transcription levels of gcrA , ccrM, and ntrY significantly increased in the mutants ( Figure 2 A and Figure S3A ).

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The results indicated that transcripts of the ntrX gene significantly increased in cells cultured in LB/MC broth containing IPTG for 2 h compared to the cells without IPTG treatment; meanwhile, the transcripts of ctrA , gcrA, and ntrY showed a decreasing trend, while the transcripts of dnaA and ftsZ1 genes increased ( Figure 2 C).

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