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Dupilumab Improves Skin Barrier Function in Adults with Atopic Dermatitis: A Prospective Observational Study.

J Clin Med · 2022 · PMC9225017 · PMID 35743415

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a decreasing trendno p-value reported
found reported a decreasing trend in SCH values in 30 patients with AD after 8 weeks of treatment [ 46 ] while Furuhashi et al. found that SCH did not change after 24 weeks of dupilumab treatment in seven patients [ 47 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.