Moreover, at all time points, a statistically significant enhancement of tissue metabolic activity was observed in comparison to the basal levels at day 0 ( $$$ p < 0.001 for day 1 versus day 0 and day 6 versus day 0, $$ p < 0.01 for day 3 versus day 0), indicating an increasing trend over time.
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Human Osteochondral Explants as an Ex Vivo Model of Osteoarthritis for the Assessment of a Novel Class of Orthobiologics.
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