Efficacy and safety of urate-lowering agents in asymptomatic hyperuricemia: systematic review and network meta-analysis of randomized controlled trials.

BMC Nephrol · 2022 · PMC9229855 · PMID 35739495

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failed to reach significanceno p-value reported

Pairwise Meta-analysis Allopurinol and febuxostat both reduced the number of renal events but this failed to reach significance relative to the placebo/no ULT (RR 0.42, 95% CI 0.17 to 1.02, and RR 0.69, 95% CI 0.46 to 1.02, respectively) (Additional file: Figure S 1 ).

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