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Design of an L-Valine-Modified Nanomicelle-Based Drug Delivery System for Overcoming Ocular Surface Barriers.

Pharmaceutics · 2022 · PMC9230556 · PMID 35745853

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a decreasing trendno p-value reported
As shown in Figure 8 , the cumulative release of BC from solution showed a decreasing trend after reaching the maximum at 3 h, while that of BC from nanomicelles remained unchanged from 4 h to 12 h, indicating that BC was unstable in PBS (pH 6.0), while it was continuously released from nanomicelles to maintain drug concentration.

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