Compound 27 shows extremely significant and broad-spectrum cytotoxicity against a series of cell lines with the IC 50 values at the nM level, and compounds 46 and 49 − 51 display potent and broad-spectrum cytotoxicity ( Table 3 ).
1
—
—
Compound 27 shows extremely significant and broad-spectrum cytotoxicity against a series of cell lines with the IC 50 values at the nM level, and compounds 46 and 49 − 51 display potent and broad-spectrum cytotoxicity ( Table 3 ).