highly significantP < 0.0001
The Adonis test confirmed the highly significant association of virome composition with hive and location ( P < 0.0001 by an Adonis-Bray test; R 2 , 0.62964 and 0.45389). k-means clustering had for k 13 (representing hives) an adjusted mutual information score (taking on values from 1 for identical to around 0 for random) of 0.14, suggesting the existence of a pattern in clustering ( Fig.