Results indicated the assembly of heteromeric GlyRs in the cytoplasm for WT and mutant receptors with a nonsignificant trend indicating a possible increased affinity of the GlyR β A455P subunit toward GlyR α 1 in comparison to the WT receptor ( Fig.
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Clinical, genetic, and functional characterization of the glycine receptor β-subunit A455P variant in a family affected by hyperekplexia syndrome.
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