The dosage of TRP metabolite revealed an increasing trend in kynurenic acid (KYNA) level 3 h post-BBBO but then a significant decrease is observed between 3-h (0.31 ± 0.13 μM) and 2-days (0.14 ± 0.4 μM) after BBBO and finally a stabilization.
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First Metabolomic Signature of Blood-Brain Barrier Opening Induced by Microbubble-Assisted Ultrasound.
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