Integrative molecular profiling identifies two molecularly and clinically distinct subtypes of blastic plasmacytoid dendritic cell neoplasm.

Despite the results from our MutSigCV analysis in which PDGFRA mutations were shown to be events of only borderline significance ( p = 0.05), we found a pathobiological relevance of these mutations reflected in its simultaneous significant upregulation, contributing to the phenotype of BPDCN.

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