Systematic inference of indirect transcriptional regulation by protein kinases and phosphatases.

PLoS Comput Biol · 2022 · PMC9255832 · PMID 35731801

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 10 −10actually significant

Despite the small size of the validation set (412 d ( P , T ) and 694 d ( P , P ) interactions), representing only 1% of the possible secondary regulatory interactions, PhosTF predicted 40% of the known d ( P , T ) and 28% of known d ( P , P ) interactions, which was highly significant ( p < 10 −10 ) when compared to the rate of predictions overall (20% and 18% respectively).

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