Protein analysis Protein level of IQGAP1 showed a highly significant increase in DEN-treated group (4 weeks) as compared to normal controls while p53 protein level was significantly decreased in DEN-treated group as compared to the control ( Figure 4b-c ).
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New Approach about the Signaling Crosstalk between IQGAPs/ NF- κB/IL-8 and PDCD5/p53/TRAIL Pathways that Modulate Malignant Transformation in Hepatocellular Carcinoma.
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