Goal-Directed Fluid Therapy Based on Pulse-Pressure Variation Compared with Standard Fluid Therapy in Patients Undergoing Complex Spine Surgery: A Randomized Controlled Trial.

Asian Spine J · 2022 · PMC9260406 · PMID 33966364

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

marginally significantp =0.058so close (0.05 < p ≤ 0.1)

In the subgroup analysis including more invasive surgical procedure (laminectomies involving more than three levels of instrumentation and laminectomies with tumor removal), the results remain robust, except for the postoperative bowel ileus that GDT provided promising result with marginally significant effect ( p =0.058) ( Supplement 1 ).

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