Central nervous system depressant activity of <i>Jatamansi</i> (<i>Nardostachys jatamansi</i> DC.) rhizome.

etamine.[ 8 ] Alcoholic extract of Jatamansi root increased the level of GABA on acute administration and increased the levels of most of the central biogenic amines and inhibitory neurotransmitters on chronic administration.[ 27 ] Thus, earlier studies indicate isolated compounds or extracts exert highly significant sedative activity while data of this study indicates crude form of drug administered in recommended dose produced comparatively mild CNS depressant activity.

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