The transcription factor network of E. coli steers global responses to shifts in RNAP concentration.

Nucleic Acids Res · 2022 · PMC9262627 · PMID 35748858

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may be significantno p-value reported

In detail, first, we could not find evidence of GRs (including σ 38 ) and (p)ppGpp being material in the global mid-term behaviour (although (p)ppGpp may be significant in the short-term response).

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a weak trendno p-value reported

This could explain why, when plotting |LFC| against the RNAP concentration, there is a weak trend towards increased slope with K TF ( Supplementary Figures S20C and S21 ).

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