Preferential Antibody and Drug Conjugate Targeting of the ADAM10 Metalloprotease in Tumours.

Cancers (Basel) · 2022 · PMC9264901 · PMID 35804938

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a slight trendno p-value reported

8C7-ADCs also appeared well-tolerated at the concentrations used in our experiments, with only a slight trend of weight loss in mice treated with PBD ADCs (both 8C7 and control IgG), indicating minimal non-antigen-related uptake in normal tissues.

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