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Prevalence of Congenital Anomaly and Its Relationship with Maternal Education and Age According to Local Development in the Extreme South of Brazil.

Int J Environ Res Public Health · 2022 · PMC9265685 · PMID 35805738

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an increasing trendno p-value reported
[ 26 ] identified twelve subgroups of CA with an increasing trend, among them congenital heart defects, and other subgroups with a decrease, such as microcephaly, patent ductus arteriosus, congenital hydronephrosis, and limb reduction.

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