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Global Trends in the Proportion of Macrolide-Resistant Mycoplasma pneumoniae Infections: A Systematic Review and Meta-analysis.

JAMA Netw Open · 2022 · PMC9274321 · PMID 35816304

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a decreasing trendno p-value reported
In the Western Pacific region, the proportion of MRMP infections associated with A2063G showed an increasing trend with time, whereas the proportion of MRMP infections associated with A2064G showed a decreasing trend with time ( Figure 3 B and C; eTable 5 in the Supplement ).

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an increasing trendno p-value reported
The global patterns in the proportion of MRMP infections showed an increasing trend with regional differences.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.