Helicobacter pylori may participate in the development of inflammatory bowel disease by modulating the intestinal microbiota.

Chin Med J (Engl) · 2022 · PMC9276318 · PMID 35234697

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an increasing trendno p-value reported

pylori infection, and the average relative abundance of Firmicutes showed an increasing trend in the group with previous H . pylori infection compared with the H . pylori -negative group.

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a decreasing trendno p-value reported

pylori infection has presented a decreasing trend (eg, in Hangzhou, China, the prevalence of H. pylori infection in juvenile individuals decreased from 21.6% to 17.2% between 2007 and 2014).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.