The average hospital monthly purchase spending of priceregulated antibiotics also decreased rapidly (β=-0.49, P <.010) and a positive trend change (β=0.04, P <.001) in average hospital spending of price-unregulated antibiotics was found.
At 12 months after the regulation, there was an estimated reduction in the average daily cost for price-regulated drugs of -5.56 ( P < .001), with significant decline relative to price-unregulated drugs (level change β = -5.41, P < .001). Influence of Government Regulation on Average Purchase Volumes From January 2011 to March 2015, the average purchase volumes of price-regulated drugs demonstrated an increasing trend while the average purchase volumes of price-unregulated drugs basically remained stable relative to the price-unregulated group ( Figure 2 ).