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Genital microbiota of women using a 90 day tenofovir or tenofovir and levonorgestrel intravaginal ring in a placebo controlled randomized safety trial in Kenya.

Sci Rep · 2022 · PMC9283538 · PMID 35835755

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a decreasing trendno p-value reported
There was a decreasing trend in microbial diversity with increased TFV concentration, with a 84.6-fold higher TFV concentration found with an L. crispatus -dominant microbiota (CST I) compared to a more diverse BV-associated microbiota (CST IVB).

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