Clearance of oxytocin and its potentially enzyme resistant analogues in the OXT-receptor compartment of the potassium depolarized rat myometrium.

Values of descriptors κ (left‐hand side) are predominantly determined by substituents in position 1 (p1; see Figure 1 ) that are in all instances highly significant ( p ≤ 0.01): polar groups (NH 2 or OH) contribute positively to κ , their omission leads to significantly more negative φ descriptors.

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