a nonsignificant trendp = .08
The meta‐analysis found that colchicine use was associated with a 56% decrease in the composite CV outcome ( p = .0004), as well as a nonsignificant trend toward reduction in all‐cause mortality (relative risk 0.50, p = .08). 11 Several additional retrospective studies have also demonstrated favorable CV outcomes with the use of colchicine. 13 , 14 Recently, prospective, randomized, and placebo‐controlled trials have also examined the potential benefit of colchicine in CV patients.