Barely Significant
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Association of colchicine use for acute gout with clinical outcomes in acute decompensated heart failure.

Clin Cardiol · 2022 · PMC9286335 · PMID 35481608

1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

a nonsignificant trendp = .08so close (0.05 < p ≤ 0.1)
The meta‐analysis found that colchicine use was associated with a 56% decrease in the composite CV outcome ( p = .0004), as well as a nonsignificant trend toward reduction in all‐cause mortality (relative risk 0.50, p = .08). 11 Several additional retrospective studies have also demonstrated favorable CV outcomes with the use of colchicine. 13 , 14 Recently, prospective, randomized, and placebo‐controlled trials have also examined the potential benefit of colchicine in CV patients.

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