ChREBP-driven DNL and PNPLA3 Expression Induced by Liquid Fructose are Essential in the Production of Fatty Liver and Hypertriglyceridemia in a High-Fat Diet-Fed Rat Model.

Mol Nutr Food Res · 2022 · PMC9286604 · PMID 35124887

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marginally significantno p-value reported

[ 41 , 42 ] We detected a marginally significant increase in the expression of DAGT2 in the livers of HFHFr rats, indicating that the increased amount of newly formed fatty acids is not matched with a corresponding increase in DGAT2 expression/activity, which could be responsible for the increased accretion of DAG species in the livers of fructose‐supplemented rats.

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