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Uncontrolled Extensions of Clinical Trials and the Use of External Controls-Scoping Opportunities and Methods.

Clin Pharmacol Ther · 2022 · PMC9290853 · PMID 34165790

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an increasing trendno p-value reported
Third, although we observed an increasing trend in the number of uncontrolled extensions from 2009 to 2018, this could also represent improvement in reporting of uncontrolled extensions over the years.

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