Safety, pharmacokinetics and quantitative EEG modulation of TAK-071, a novel muscarinic M1 receptor positive allosteric modulator, in healthy subjects.

Br J Clin Pharmacol · 2022 · PMC9291057 · PMID 34240455

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marginal significanceno p-value reported

However, the placebo + donepezil group showed marginal significance of reduced functional connectivity (Figure 4B ) that mostly involved beta band synchronization.

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