The emergence of tumor-infiltrating lymphocytes in nasopharyngeal carcinoma: Predictive value and immunotherapy implications.

1 On the contrary, the age-standardized death rate (ASDR) of NPC showed a decreasing trend from 0.93 in 2009 to 0.86 in 2019 and negatively correlated with social demographic index (SDI) in most regions. 1 Morbidity and mortality rates of NPC have stabilized or declined in high-incidence areas.

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It's worth noting that there may be significant differences in the size and composition of TME between different cases of NPC.

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TILs play an extremely significant role in the occurrence, development, invasion and metastasis of NPC.

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