Statistical challenges in longitudinal microbiome data analysis.

Brief Bioinform · 2022 · PMC9294433 · PMID 35830875

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an overall trendno p-value reported

This framework includes three methods: the first method tests for the overall difference between two groups over the full time course, the second method tests for the difference between two groups at defined intervals to identify regions of time with group differences, and the third method tests for an overall trend in a single population over time.

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