Innate Immune Response in Respiratory System: A Double-edged Sword Against Virus Infection.

Infect Dis Immun · 2022 · PMC9295932 · PMID 37520107

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A highly significant feature is the cytokine release syndrome (CRS), patients who developed into critical status commonly display an uncontrolled and life-threatening host immune responses concomitant with markedly elevated serum proinflammatory cytokines and chemokines, such as IL-6, IL-8, TNF-α, CCL2, CCL5, and CXCL10.

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