A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients.

By this procedure, a highly significant correlation between HF W-m and the pathologist’s hypoxia score in 100 patients was obtained (r = 0.78; P < 0.001, Supplementary Methods S1 ).

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Notably, the correlation with HF W-m for the Yang-signature was on the borderline of significance, whereas no correlation was found between the Yang- and the Ragnum-signature (Supplementary Table S2 ).

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