Barely Significant
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Difamilast, a selective phosphodiesterase 4 inhibitor, ointment in paediatric patients with atopic dermatitis: a phase III randomized double-blind, vehicle-controlled trial.

Br J Dermatol · 2022 · PMC9298328 · PMID 34289086

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highly significantno p-value reported
Patients in the difamilast 0·3% and difamilast 1% groups also showed highly significant success rates in IGA score compared with the vehicle group at weeks 1 and 2 (Figure 2 ).

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