The sequestration of miR‐185‐5p with its inhibitor increased almost significantly the expression of POSTN (fold of 1.50 ± 0.57; p = 0.05; Figure 1c ) in BSMCs; an increase which was maintained after IL‐13 addition (fold of 1.13 ± 0.06, p < 0.05; Figure 1c ).
In SAECs, inhibition of miR‐185‐5p causes a mild upregulation, which is nonsignificant (fold of 1.14 ± 0.09; p > 0.05; Figure 1d ), being this increase almost significant in the SAECs treated with IL‐13 (fold of 1.22 ± 0.10; p = 0.08; Figure 1d ), which might indicate that IL‐13 treatment could enhance the effect of the inhibitor of miR‐185‐5p by augmenting POSTN expression in absence of miR‐185‐5p.