Barely Significant
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A phase 1 multiple-ascending dose study of tirzepatide in Japanese participants with type 2 diabetes.

Diabetes Obes Metab · 2022 · PMC9299227 · PMID 34647404

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a decreasing trendno p-value reported
12 In the current study, we found a decreasing trend in fullness (the physical sensation of how much the stomach is filled with food), and no difference in appetite scores among treatment groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.