Still, small changes in chiroptical spectra can be highly significant if they coincide with a physical model describing the underlying dynamic process, as recently demonstrated for the global analysis of spectral changes occurring over time, [20] in response to pH, [21] ligand binding, [22] or chemical modification.
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Dynamic Structural Changes and Thermodynamics in Phase Separation Processes of an Intrinsically Disordered-Ordered Protein Model.
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