Barely Significant
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Current Applications of Fecal Microbiota Transplantation in Functional Constipation.

Evid Based Complement Alternat Med · 2022 · PMC9300281 · PMID 35873640

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an increasing trendno p-value reported
[ 9 ] first used 16SrRNA to study the intestinal flora of FC children and found a significant decrease in Prevotella and an increasing trend in the thick-walled phylum.

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a decreasing trendno p-value reported
administered a total of 3 courses of FMT (1 time/d for 6 d, repeating a course after 1 and 3 months) to patients with FC, assuming complete spontaneous defecation ≥ 3 times as the criterion for clinical remission, with a decreasing trend in remission rates from week 4 onwards, again confirming that short-term efficacy (4 weeks) was superior to long-term efficacy (1 year) [ 24 ].

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