Population Pharmacokinetics and Exposure-Response Relationships of Astegolimab in Patients With Severe Asthma.

J Clin Pharmacol · 2022 · PMC9303772 · PMID 34964491

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a slight trendno p-value reported

A decrease in eosinophil levels over time was indicated with a slight trend of separation between placebo and exposure tertiles.

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a weak trendno p-value reported

The exposure‐response of efficacy and biomarkers were generally flat with a weak trend in favor of the highest dose/exposure.

also in 1,404 other papers

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