Blocking cell cycle progression through CDK4/6 protects against chronic kidney disease.

JCI Insight · 2022 · PMC9309053 · PMID 35730565

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a nonsignificant trendno p-value reported

The CyclinD1 CKO mice had a nonsignificant trend toward increased STAT3 expression and activation ( Supplemental Figure 4 ), and the exact mechanism of exacerbated tubular injury is beyond the scope of this study.

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