Age-dependent gray matter demyelination is associated with leptomeningeal neutrophil accumulation.

When examining the brain parenchyma (cortex and brainstem), we only noted a significant decrease in B cells, a slight trend toward increase in frequency and absolute number of neutrophils, and no difference in frequencies or absolute number of monocytes ( Supplemental Figure 4 and Supplemental Figure 5 , B–H).

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