85 There was no difference in OS based on their primary analysis, but calculation of OS from date of initial therapeutic intervention showed a nonsignificant trend to worse OS in those who had preoperative chemotherapy consistent with other literature suggesting this association. 9 , 12 , 35 , 75 , 78 , 83 , 92 However, in this study, there was a high response rate to chemotherapy of 58%, and no patient experienced disease progression.
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The role of chemotherapy in the treatment of advanced appendiceal cancers: summary of the literature and future directions.
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