Irisin Attenuates Muscle Impairment during Bed Rest through Muscle-Adipose Tissue Crosstalk.

Δ Irisin was inversely associated with Δ CSA of Fiber Slow/1, both percentage ( r −0.559; P value 0.007) ( Figure 2 B) and absolute ( r −0.614; P value 0.002), and almost significantly negatively associated with absolute CSA variation of fiber type 2 ( r −0.395; P value 0.062) ( Supplementary Materials, Table S4 ).

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